Whole exome sequencing opens new ground in pharmacogenomics
A whole exome sequencing workflow now lets researchers analyze both coding and non-coding variants tied to drug response and safety, pushing past the limits of targeted panels.
Exome sequencing 1 article
In biotechnology workflows, exome sequencing functions as a targeted coding-region sequencing method built around coding region sequencing. Its defining logic links exome capture and hybridization enrichment with protein-coding exons, while rare variant detection, germline variant analysis and somatic variant analysis indicate the measurements, molecular events or applications most closely associated with the entity. The tag describes the method itself, not a sequencing company or named instrument; its identity is anchored by coding region sequencing rather than by the hardware used to generate the data.