Single CRISPR infusion cuts stubborn LDL cholesterol for a year
A single dose of CTX310, a CRISPR-Cas9 therapy, dropped LDL cholesterol by more than half in patients who did not respond to standard drugs. The effect lasted at least a year.
CRISPR-Cas9 5 articles
RNA-guided DNA cleavage defines CRISPR-Cas9 as an RNA-guided DNA editing system. The concept combines this feature with Cas9 endonuclease and single-guide RNA, then extends through programmable genome editing, double-strand DNA breaks and PAM recognition to support or explain targeted gene knockout. CRISPR-Cas9 therefore remains distinct from complete therapeutic constructs and from neighboring editing tools that share a workflow but perform a different molecular function.
Gene editing strategies take center stage in malaria research at MDU
MDU's Centre for Biotechnology brought leading scientists to campus to dissect how gene editing tools like CRISPR-Cas9 are reshaping malaria research and student training.
AI-designed genome editors offer new options for rice gene editing
Researchers at ICAR-Central Rice Research Institute have shown that Plant OpenCRISPR-1, an AI-designed genome editor, works as well as established systems for editing rice genes.
Gene edited rice faces backlash as coalition demands urgent policy reversal in India
A coalition of scientists and farmers is urging the Indian government to stop gene edited rice, warning of health, environmental, and economic risks, and calling for a return to Dr Richharia’s sustainable approach to agriculture.
Gene edited rootstock offers hope for Florida citrus survival
Florida citrus growers are betting on gene edited rootstock to fight a bacterial disease that has decimated their groves and production.