Single-cell RNA sequencing 1 article

Single-cell RNA sequencing measures transcript abundance separately in individual cells rather than averaging expression across a bulk sample. Cell barcodes and molecular identifiers link sequencing reads back to their cell of origin, producing gene-by-cell count matrices used to resolve cell types, states, rare populations and transcriptional heterogeneity. The tag refers specifically to RNA profiling at single-cell resolution, not to single-cell sequencing broadly or to a branded droplet platform used for capture.