Reporting from the frontiers of health and medicine

Travere CEO Eric Dube steps down after Filspari breakthrough

Travere CEO Eric Dube steps down after Filspari breakthrough GenoMethods.org © genomethods.org
Travere CEO Eric Dube steps down after Filspari breakthrough © genomethods.org
Eric Dube is leaving his post as CEO of Travere Therapeutics after leading the company through a major rebrand and the launch of Filspari. Bradley Campbell will step in as the company rides a wave of growth in rare kidney disease treatments.

Travere Therapeutics is changing leadership. Eric Dube, Ph.D., who led the company’s turnaround and brought Filspari to market, is stepping down as CEO to focus on his health and family. Under Dube, Travere’s rare kidney disease drug Filspari won both accelerated and full FDA approval. Now, Bradley Campbell, a veteran in rare disease biotech, will take over.

Dube leaves after nearly eight years in charge. During his time, he rebranded the company from Retrophin, moving it away from its ties to founder Martin Shkreli. He also guided Travere through tough regulatory hurdles to get Filspari to patients with immunoglobulin A nephropathy (IgAN) and, more recently, focal segmental glomerulosclerosis (FSGS).

In September 2026, Eric Dube sold approximately $25.4 million worth of Travere shares in transactions that occurred just days before the public announcement of his planned CEO departure.

Investing.com

“My own experiences with rare disease have also given me a profound appreciation for health, family and time,” Dube said. He is a two-time rare cancer survivor. In a LinkedIn post, he wrote about the toll of constant advocacy and said, “I’ve decided it’s time for me to listen more closely to that lesson.”

The board picked Campbell, who led Amicus Therapeutics through its $4.8 billion sale to BioMarin, to become CEO on December 1, 2026. Dube will stay on as executive advisor until February 2027 to help with the handover. Board chairman Gary Lyons pointed to Campbell’s mix of scientific, commercial, and operational experience as the main reason for his selection. Lyons said Campbell has shown he can drive growth and move clinical programs forward. According to an official company press release, Campbell will also join Travere's board of directors on December 1, 2026.

Campbell steps in as Travere is growing fast. In the second quarter, U.S. sales of Filspari nearly doubled from a year earlier, hitting $141 million and beating analyst forecasts for the FSGS launch. Competition is heating up. Vertex’s povetacicept is aiming for an FDA decision in November 2026, and more companies are entering the IgAN market. Travere has also expanded its pipeline, paying $112.5 million upfront to buy civorebrutinib from Everest Medicines for work on immune-mediated kidney diseases.

Travere Therapeutics confirmed that Eric Dube will remain CEO until December 1, 2026, after which he will serve as executive advisor through February 15, 2027, to ensure an orderly leadership transition.

Travere TherapeuticsCompany press release

“I see an exciting opportunity to build on that momentum, reach more people living with rare disease and continue creating meaningful value for all stakeholders,” Campbell said. He plans to build on Travere’s culture and recent wins.

Dube leaves behind a company transformed by the launch and growth of Filspari. Now, Travere faces the challenge of keeping up its pace under Campbell. The company’s future will depend on how well it can deliver on both regulatory and commercial goals in a crowded rare disease market. This leadership change is a calculated move to keep Travere’s momentum going at a time when timing and execution matter most.

Markets reacted quickly to the news. Travere shares fell after the CEO transition was announced, according to MarketWatch coverage on September 21, 2026.

Vivian Lin Biotech markets and transactions editor GenoMethods.org
Biotechnology Newsroom

Vivian Lin

Vivian Lin is Biotech Markets & Transactions Editor at GenoMethods, covering licensing agreements, M&A, biotech financing, company pipelines, strategic partnerships and cross-border transactions. Her reporting connects deal structure and company strategy with the scientific and clinical evidence underlying each biotechnology asset.